UCL 2077( —— )

Catalog No. M26857 CAS No. 918311-87-2

UCL 2077 is a subtype-selective blocker of the epilepsy-associated KCNQ channels and it also is a selective slow-afterhyperpolarization channel blocker.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	215	Get Quote
25MG	389	Get Quote
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100MG	801	Get Quote
500MG	1647	Get Quote
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Biological Information

Product Name

UCL 2077
Note

Research use only, not for human use.
Brief Description

UCL 2077 is a subtype-selective blocker of the epilepsy-associated KCNQ channels and it also is a selective slow-afterhyperpolarization channel blocker.
Description

UCL 2077 is a subtype-selective blocker of the epilepsy-associated KCNQ channels and it also is a selective slow-afterhyperpolarization channel blocker，with IC50 of 500 nM in hippocampal neurons in culture, having minimal effects on Ca2+ channels, action potentials, input resistance, and the medium afterhyperpolarization.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Bacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

918311-87-2
Formula Weight

350.465
Molecular Formula

C25H22N2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (356.67 mM)
SMILES

C(NC(c1ccccc1)(c1ccccc1)c1ccccc1)c1cccnc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Yi-Ping Chin, et al. Synthesis and evaluation of antibacterial activities of 5,7-dihydroxycoumarin derivatives. Arch Pharm (Weinheim). 2011 Jun;344(6):386-93.

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